Thermo Fisher Scientific 5HT3D R/5HT3E R Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

-

Immunohistochemistry (IHC)

1:300-1:2,000

-

Miscellaneous PubMed (Misc)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from c-terminal region of human 5HT3D receptor (Serotonin receptor 3D) conjugated to an immunogenic carrier protein was used as the antigen if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HTR3D/HTR1E,uniProtId:Q70Z44-1,ncbiNodeId:9606,antigenRange:454,antigenLength:454,antigenImageFileName:OSS00194W-100UL_HTR3DHTR1E_Q70Z44-1_Rabbit.svg,antigenImageFileNamePDP:OSS00194W-100UL_HTR3DHTR1E_Q70Z44-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in 5HT3E.

Specificity of this antibody: 5HT3D, 5HT3E receptors.

Target Information

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. Tissue Specificity: 5HT3D: Expressed in liver, as well as fetal and adult colon and kidney. 5HT3E: Expressed in adult colon and intestine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.