Thermo Fisher Scientific 5HT5B R Polyclonal Antibody
Thermo Fisher Scientific의 5HT5B R Polyclonal Antibody는 마우스 5HT5B 수용체를 인식하는 토끼 다클론 항체입니다. Western blot과 IHC에 적합하며, 리오필라이즈 형태로 제공됩니다. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of mouse 5HT5B receptor (Serotonin receptor 5B) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: 5HT5B receptor.
Target Information
SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT).
Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract.
Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality, and appetite.
Rat SR-5B is present in serotonergic neurons in the dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus).
DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus.
CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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