Thermo Fisher Scientific CD147 Polyclonal Antibody

Applications

Tested Dilution

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

• Positive test controls: HepG2, Mouse lung, Mouse brain, Rat lung
• Localization: Cell membrane, Melanosome, Single-pass type I membrane protein
• Immunogen sequence:
  HIENLNMEAD PGQYRCNGTS SKGSDQAIIT LRVRSHLAAL WPFLGIVAEV LVLVTIIFIY EKRRKPEDVL DDDDAGSAPL KSSGQHQNDK GKNVRQRNSS

Target Information

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 belongs to the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
Functions include:

• Facilitating cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases
• Regulating integrin functions
• Playing roles in cell development and activation, fetal development, and retinal function

주의사항

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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