Thermo Fisher Scientific Phospho-PDGFRA (Tyr1018) Polyclonal Antibody
인간 PDGFRA(Y1018) 인산화 형태를 인식하는 Rabbit Polyclonal 항체로 Western Blot과 ELISA에 적합. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around Y1018 of human PDGFRA (NP_0061971) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901837 |
Product Specific Information
- Positive Samples: HepG2 + UV, HepG2 + EGF
- Immunogen sequence: SGYII
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The specific growth factor bound determines whether the receptor forms a homodimer or heterodimer (composed of alpha and beta polypeptides).
Knockout mouse studies show that the alpha form is critical for kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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