Thermo Fisher Scientific Phospho-LKB1 (Ser334) Polyclonal Antibody
Phospho-LKB1 (Ser334) 특이적 폴리클로날 항체로, Western blot 및 ELISA에 적합. 인간, 마우스, 랫트 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며, -20°C에서 안정적.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S334 of human STK11 (NP_0004461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901835 |
Product Specific Information
- Positive Samples: HeLa
- Immunogen sequence: WRSMT
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is found in both cytoplasm and nucleus and translocates to mitochondria during apoptosis.
It functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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