Thermo Fisher Scientific OX40L (CD252) Polyclonal Antibody
OX40L(CD252)에 특이적인 Rabbit Polyclonal Antibody로 Mouse 및 Rat 시료에 반응. WB, IHC, ELISA 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 순도 제공. 연구용으로 면역반응 및 세포 활성 연구에 적합.
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- PA580169
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- pk
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Thermo Fisher Scientific OX40L (CD252) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC(P)) | 0.5–1 µg/mL | - |
| ELISA | 1–5 µg/mL (capture) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse CD252 recombinant protein (Position: Q49–L198) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2747283 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane-bound, non-covalently linked homotrimeric protein.
It is expressed on antigen-presenting cells such as dendritic cells and activated B-cells, as well as on vascular endothelial cells, mast cells, and natural killer cells.
TNFSF4 signals specifically through the TNFRSF4 receptor, which is expressed predominantly on CD4+ T cells and certain activated CD8+ T cells.
TNFRSF4/TNFSF4 interaction provides a costimulatory signal essential for effective communication between antigen-presenting cells and T cells, enhancing proliferation, survival, and cytokine expression (RANTES, IL-2, IL-3, IFN-γ).
This signaling pathway plays a critical role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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