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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody (PDL1, 2746)
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PD-L1 단백질을 인식하는 단클론 항체로, 암 면역치료 연구에 적합. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 인간 및 생쥐 시료 반응성. Protein A/G 정제, 액상 형태, 4°C 보관.
- 카탈로그번호
- 29126-MSM6-P1
- 판매단위
- pk
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Thermo Fisher Scientific 29126-MSM6-P1 PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody (PDL1, 2746) 100 ug pk판매 단위 pk ·
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825,100원VAT 포함 907,610원
Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody (PDL1, 2746)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PDL1, 2746 |
| Immunogen | Recombinant fragment (around aa 39–191) of human CD274 (PD-L1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues, heat sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes before staining.
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family. Its receptor, PD-1, negatively regulates T-cell receptor (TCR) signaling. PD-L1 binding to PD-1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and is upregulated upon IFN-γ stimulation, suggesting a key role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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