Thermo Fisher Scientific KCNQ3 Polyclonal Antibody
Rabbit polyclonal antibody against KCNQ3 for WB and IHC applications. Reacts with human, mouse, and rat. Lyophilized form, reconstitute in sterile water. Specific for KCNQ3, useful for neuroscience and ion channel research.
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- OSK00071W-100UL
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 60–120 of mouse KCNQ3 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in human and rat.
- Specificity: KCNQ3.
Target Information
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. There are five known KCNQs (KCNQ1–5) found in the central nervous system. KCNQ2 and KCNQ3 play key roles in M-current activation and form heteromultimers that increase M-current. Inhibition of M-current regulates neuronal excitability and synaptic responsiveness. Mutations in these proteins are associated with benign familial neonatal convulsions (BFNC), deafness, neuropathic pain, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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