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Thermo Fisher Scientific IMP4/SPPL2B Polyclonal Antibody
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Western blot, IHC, ICC 등 다양한 응용에 적합한 Rabbit Polyclonal Antibody. Human, Mouse, Rat 반응성. SPPL2B 유래 합성 펩타이드 면역원 사용. 단백질 A 정제, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- BS-11682R
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 10:28
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Thermo Fisher Scientific BS-11682R IMP4/SPPL2B Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
531,800원VAT 포함 584,980원
Thermo Fisher Scientific · Thermo Fisher Scientific IMP4/SPPL2B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SPPL2B (amino acids 55–135) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPPL2B is a member of the GXGD family of aspartic proteases. These transmembrane proteins have two conserved catalytic motifs localized within membrane-spanning regions. SPPL2B localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha (TNF-α), releasing the intracellular domain that triggers cytokine expression involved in innate and adaptive immunity pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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