Thermo Fisher Scientific GPR55 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GPR55 for IHC applications. High specificity and purity by antigen affinity chromatography. Supplied as liquid form at 1 mg/mL in PBS with sodium azide. Suitable for neuroscience and GPCR research.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminus of human GPR55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551107 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey (100%)
Panda (85%)
Marmoset, Bovine, Elephant, Horse (80%)
Target Information
GPR55 is expressed in the brain, with mRNA transcripts detected in the caudate nucleus and putamen, but not in five other brain regions (Sawzdargo et al., 1999). ESTs have been isolated from liver/spleen libraries.
G-protein Coupled Receptors (GPCRs) constitute one of the largest families of signaling molecules, sharing a common structure of seven membrane-spanning helices. They exist in active and inactive forms and are regulated through complex signaling pathways involving G-proteins and downstream effectors.
GPCRs play key roles in pharmacological research, with notable drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) developed as GPCR-targeted pharmaceuticals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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