Thermo Fisher Scientific OAS2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-3 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL

-

Immunocytochemistry (ICC/IF)

5-30 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein 2,5-Oligoadenylate Synthetase 2. The antigen corresponds to amino acid range 11-346 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OAS2,uniProtId:P29728-1,ncbiNodeId:9606,antigenRange:11-346,antigenLength:719,antigenImageFileName:PA5-118919_OAS2_P29728-1_Rabbit.svg,antigenImageFileNamePDP:PA5-118919_OAS2_P29728-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2903419

Target Information

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5`-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.