Thermo Fisher Scientific CDK5 Monoclonal Antibody (8A1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

-

Immunocytochemistry (ICC/IF)

1:250

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

2 µL

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

8A1

Immunogen

Purified, His-tagged, recombinant, human CDK5 protein, from baculovirus expressed insect cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_1073560

Product Specific Information

A suggested positive control for this product is SH-SY5Y cells.

Target Information

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.