Thermo Fisher Scientific GPNMB Recombinant Rabbit Monoclonal Antibody (105)
Human GPNMB/Osteoactivin 단백질을 인식하는 recombinant rabbit monoclonal antibody. ELISA에 적합하며 높은 특이성과 재현성을 제공. 보존제가 없는 액상 형태로 공급되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 105 |
| Immunogen | Recombinant Human GPNMB/Osteoactivin Protein (Met1–Pro474) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term); -20°C (long term). Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786200 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to prevent contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, and the best clones are selected for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
This antibody specifically recognizes Human GPNMB/Osteoactivin.
Target Information
The GPNMB gene encodes a type I transmembrane glycoprotein homologous to the melanocyte-specific pMEL17 precursor. GPNMB is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic lines. It may play a role in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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