Thermo Fisher Scientific STAT1 alpha/beta Polyclonal Antibody
STAT1 alpha/beta 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human 및 Mouse 반응성. 액상 형태로 1 mg/mL 농도이며, PBS buffer에 보관. 연구용 전용 제품.
- 카탈로그번호
- PA5119735
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STAT1 alpha/beta Polyclonal Antibody
Thermo Fisher Scientific STAT1 alpha/beta Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:100–1:200 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Stat-1 alpha/beta (76–119) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913307 |
Product Specific Information
- Positive Control: MCF-7, HeLa, NIH/3T3, HepG2, human kidney tissue, human breast cancer tissue, mouse kidney tissue
- Subcellular Location: Cytoplasm, nucleus
Target Information
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of various Stat transcription factors.
Stat1 and Stat2 are induced by IFN-α and form a heterodimer that is part of the ISGF3 transcription factor complex.
Stat3 activation occurs via EGF and IL-6, with Stat3α activated by both while Stat3β is activated by EGF only.
Highest expression of Stat4 is seen in testis and myeloid cells, activated by IL-12.
Stat5 is activated by Prolactin and IL-3, and Stat6 is involved in IL-4 signaling pathways.
Important Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.