Thermo Fisher Scientific TRPC4 Polyclonal Antibody
TRPC4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(F), IP에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 세포 내 C-말단 영역(aa 943-958)에 대한 항원 기반.
- 카탈로그번호
- ACC-018-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRPC4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunoprecipitation (IP) | 6 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KEKHAHEEDSSIDYDL, corresponding to amino acid residues 943–958 of mouse TRPC4, Intracellular, C-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution:
- Add 25 µL, 50 µL, or 0.2 mL of double-distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
TRPC4 is a member of the canonical subfamily of transient receptor potential cation channels. It forms a non-selective calcium-permeable cation channel activated by Gq-coupled receptors and tyrosine kinases. TRPC4 plays roles in endothelial permeability, vasodilation, neurotransmitter release, and cell proliferation.
Single nucleotide polymorphisms in TRPC4 may be associated with generalized epilepsy with photosensitivity.
Alternatively spliced transcript variants encoding multiple isoforms have been observed.
The TRPC family (TRPC1–7) is closely related to the Drosophila TRP channel. Diseases associated with TRPC4 include photosensitive epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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