Thermo Fisher Scientific Phospho-AKT Pan (Thr308, Thr305, Thr309) Polyclonal Antibody
AKT 단백질의 Thr308, Thr305, Thr309 인산화 부위를 인식하는 rabbit polyclonal 항체로, Western blot 및 ELISA에 적합합니다. Human 및 Mouse 시료 반응성이 있으며, 액상 형태로 -20°C 보관합니다. 세포 생존 및 신호전달 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around T308 of human AKT1 (NP_005154.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914917 |
Product Specific Information
- Positive test controls include: NIH/3T3
- Immunogen sequence: MKTFC
Target Information
AKT, also known as protein kinase B (PKB) or RAS-alpha, is a serine/threonine kinase involved in regulating metabolism, cell survival, and growth through phosphorylation of multiple proteins. It is activated by insulin, PI3K, IGF1, and other growth factors. AKT promotes cell survival by inhibiting apoptosis via phosphorylation and inactivation of targets such as forkhead transcription factors and caspase-9. The AKT pathway is a major target in cancer drug discovery.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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