Thermo Fisher Scientific SULT1A1 Polyclonal Antibody
Thermo Fisher Scientific의 SULT1A1 Polyclonal Antibody는 인간 및 생쥐에 반응하며, Western blot에 적합한 rabbit IgG 항체입니다. KLH 결합 합성 펩타이드로 면역화되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 128–160 amino acids from the central region of human SULT1A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation, Size-exclusion - Dialysis |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2197591 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens, and the regulation of hormones by catalyzing the sulfate conjugation of these substances.
Members of the three groups comprising this superfamily (SULT1, SULT2, and SULT3) show selectivity to certain substrate compounds.
SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family.
Functioning as a homodimer expressed in brain, liver, skin, and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters, playing a role in the elimination of various compounds from the body.
Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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