Thermo Fisher Scientific DAAM1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DAAM1 protein. Validated for WB and IHC applications. Purified by Protein A and antigen affinity chromatography. Supplied as liquid form with PBS buffer and sodium azide preservative. Suitable for research use...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 1034–1063 from the C-terminal region of human DAAM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2089439 |
Target Information
DAAM1 (Disheveled-associated activator of morphogenesis 1) is a diaphanous-related formin that binds Disheveled and plays a key role in planar cell polarity signaling in Xenopus. It regulates actin filament nucleation and elongation through its FH2 domain and is controlled by RhoA signaling. DAAM1 is involved in neuronal development and gastrulation processes. Structurally, it includes GTPase-binding (GBD), diaphanous inhibitory (DID), coiled-coil, FH1, FH2, and diaphanous auto-regulatory (DAD) domains. The human DAAM1 gene is located on chromosome 14q23.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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