
Thermo Fisher Scientific SULT2A1 Polyclonal Antibody
Thermo Fisher Scientific의 SULT2A1 Polyclonal Antibody는 인간 SULT2A1 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot에 적합합니다. 간과 부신 조직에서 발현되는 SULT2A1 연구에 활용되며, 고순도의 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): 1:1,000
View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 253–285 of the C-terminal region of human SULT2A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion chromatography, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2302776 |
Target Information
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids. SULT3 family members are selective for N-substituted aryl and alicyclic compounds.
SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues. It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulfation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol. SULT2B1b is expressed in prostate, skin, placenta, and lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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