Thermo Fisher Scientific CYP2E1 Monoclonal Antibody (OTI9E6), TrueMAB
Thermo Fisher Scientific의 CYP2E1 단클론 항체(OTI9E6)는 인간 CYP2E1 단백질을 인식하는 마우스 IgG1 항체로, WB, IHC, ICC/IF 등에 사용 가능. 동결건조 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 연구용으로 약물 대사 및 간질환 관련 연구에 적합.
- 카탈로그번호
- CF500735
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9E6 |
| Immunogen | Full length human recombinant protein of human CYP2E1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CYP2E1 is a member of the cytochrome P450 enzyme superfamily. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This enzyme localizes to the endoplasmic reticulum and is induced by ethanol, diabetic states, and starvation.
It metabolizes endogenous substrates (ethanol, acetone, acetal) and exogenous substrates (benzene, carbon tetrachloride, ethylene glycol, nitrosamines).
Due to its broad substrate range, CYP2E1 is implicated in processes such as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: CF500735_CYP2E1_P05181-1_House_mouse.svg, CF500735_CYP2E1_P05181-1_House_mouse_PDP.jpeg)
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