Thermo Fisher Scientific ERK3 Polyclonal Antibody
ERK3(MAPK6) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. 사람, 마우스, 랫트 시료 반응. 합성 펩타이드 항원을 이용해 제작되었으며, 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAPK6 (Accession Q16659), corresponding to amino acid residues E163–I213. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850621 |
Product Specific Information
Antibody detects endogenous levels of total MAPK6/ERK3.
Target Information
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), are activated through phosphorylation cascades and serve as integration points for multiple biochemical signals. This kinase is localized in the nucleus and is activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in skeletal muscle, followed by brain. Also expressed in heart, placenta, lung, liver, pancreas, kidney, and skin fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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