Thermo Fisher Scientific CES1 Monoclonal Antibody (544623)
CES1 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 Immunoprecipitation에 적합. 인간에 반응하며, 단백질 A/G로 정제된 동결건조 형태. PBS 및 5% 트레할로스 완충액에 보관하며, -20°C에서 저장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
- View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: 25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 544623 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Carboxylesterase 1/CES-1 (His19–Glu563) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609162 |
Product Specific Information
- In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse CES-3 is observed.
- No cross-reactivity with rmCES-2, rmCES-5, or recombinant human CES-2.
- Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
This gene encodes a member of the carboxylesterase large family. Members of this family hydrolyze or transesterify various xenobiotics (e.g., cocaine, heroin) and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism and play a role in the blood-brain barrier system. This enzyme is a major liver enzyme involved in hepatic drug clearance. Mutations in this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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