Thermo Fisher Scientific SEMA4D Monoclonal Antibody (3B4)
Human SEMA4D 단백질을 인식하는 Mouse monoclonal antibody (Clone 3B4). Western blot과 ELISA에 적합하며, PBS buffer에 보존된 액상 형태. Affinity chromatography로 정제되어 연구용으로 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B4 |
| Immunogen | SEMA4D (AAH54500, 115 a.a. ~224 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
LQPLSATSLY VCGTNAFQPA CDHLNLTSFK FLGKNEDGKG RCPFDPAHSY TSVMVDGELY
SGTSYNFLGS EPIISRNSSH SPLRTEYAIP WLNEPSFVFA DVIRKSPDSPTarget Information
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development.
CD100 (also known as semaphorin 4D), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro.
CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and downregulating CD23 expression.
CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells. The protein is weakly expressed on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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