Thermo Fisher Scientific SLC7A11 Recombinant Mouse Monoclonal Antibody (A7C6-R)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:200

-

Flow Cytometry (Flow)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

A7C6-R

Immunogen

293 cell line overexpressing SLC7A11. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC7A11,uniProtId:Q9UPY5-1,ncbiNodeId:9606,antigenRange:1-501,antigenLength:501,antigenImageFileName:MA5-50633_SLC7A11_Q9UPY5-1_House_mouse.svg,antigenImageFileNamePDP:MA5-50633_SLC7A11_Q9UPY5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3093725

Product Specific Information

Positive control: HT-29 cell lysate, A549 cell lysate, HCT116 cell lysates, human pancreas tissue, HT-29, A549, NIH/3T3 cell lysates.

Predicted band size: 55 kDa

Subcellular Location: Membrane.

Target Information

SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.