
Thermo Fisher Scientific PTPRN2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로, PTPRN2 단백질을 인식합니다. Western Blot, IHC, ELISA 등에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22–242 of human PTPRN2 (NP_5708582) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.77 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805900 |
Product Specific Information
Immunogen sequence:
AAPSSVPRGR QLPGRLGCLL EEGLCGASEA CVNDGVFGRC QKVPAMDFYR YEVSPVALQR LRVALQKLSG TGFTWQDDYT QYVMDQELAD LPKTYLRRPE ASSPARPSKH SVGSERRYSR EGGAALANAL RRHLPFLEAL SQAPASDVLA RTHTAQDRPP AEGDDRFSES ILTYVAHTSA LTYPPGSRTQ LREDLLPRTL GQLQPDELSP KVDSGVDRHH LPositive Samples: SH-SY5Y, SGC-7901, Mouse pancreas, Rat pancreas
Cellular Location: Cytoplasmic vesicle, Single-pass type I membrane protein, secretory vesicle, secretory vesicle membrane, synaptic vesicle membrane
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs regulate various cellular processes including growth, differentiation, mitotic cycle, and oncogenic transformation. This receptor-type PTP possesses extracellular, transmembrane, and intracellular catalytic domains. It is closely related to PTPRN/IA-2beta and is a major autoantigen associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants encoding distinct proteins have been reported.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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