Thermo Fisher Scientific PTPRN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-242 of human PTPRN2 (NP_5708582) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPRN2,uniProtId:Q92932-1,ncbiNodeId:9606,antigenRange:22-242,antigenLength:1015,antigenImageFileName:PA5-90035_PTPRN2_Q92932-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90035_PTPRN2_Q92932-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.77 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805900

Product Specific Information

Immunogen sequence: AAPSSVPRGR QLPGRLGCLL EEGLCGASEA CVNDGVFGRC QKVPAMDFYR YEVSPVALQR LRVALQKLSG TGFTWQDDYT QYVMDQELAD LPKTYLRRPE ASSPARPSKH SVGSERRYSR EGGAALANAL RRHLPFLEAL SQAPASDVLA RTHTAQDRPP AEGDDRFSES ILTYVAHTSA LTYPPGSRTQ LREDLLPRTL GQLQPDELSP KVDSGVDRHH L; Positive Samples: SH-SY5Y, SGC-7901, Mouse pancreas, Rat pancreas; Cellular Location: Cytoplasmic vesicle, Single-pass type I membrane protein, secretory vesicle, secretory vesicle membrane, synaptic vesicle membrane

Target Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.