Thermo Fisher Scientific CD80 Monoclonal Antibody (2D10)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
605-060 | - | Thermo Fisher Scientific 605-060 CD80 Monoclonal Antibody (2D10) 100 ug pk | 재고문의 | pk | 431,000원 | - | 474,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
2-10 µg/mL
Flow Cytometry (Flow)
0.5-5 µg/10^6 cells
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
2D10
Immunogen
A recombinant protein of human CD80
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Tonsil
Cellular location: Membrane.
Target Information
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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