Thermo Fisher Scientific RanBP1 Polyclonal Antibody
Human RAN Binding Protein 1을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific RanBP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:50–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human RAN Binding Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kDa protein that binds to RAN complexed with GTP but not GDP. It does not activate GTPase activity of RAN but enhances GTP hydrolysis by RanGAP1. The RANBP1 cDNA encodes a 201-amino acid protein with 92% similarity to its mouse homolog. In both mammalian cells and yeast, RanBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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