Thermo Fisher Scientific Paxillin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Paxillin. Suitable for IHC and IHC-P applications with 1:100–1:500 dilution. Unconjugated, affinity purified, and supplied in TBS with BSA and sodium azide. Recommended storage at 4°C for 1 year. For research ...
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1 and 50 of human Paxillin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, and Little brown bat.
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. Its tyrosine phosphorylation is influenced by conditions affecting cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain, independently of the extracellular matrix. Initially discovered in fibroblasts, paxillin phosphorylation may also play a role in neurite extension during differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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