Thermo Fisher Scientific IL-2 Monoclonal Antibody (JES6-1A2)
마우스 IL-2 단백질을 인식하는 단클론 항체로, IHC(P) 및 유세포분석(Flow Cytometry)에 적합합니다. Rat IgG2a 아이소타입이며 비결합형(unconjugated) 형태로 제공됩니다. Protein A로 정제되었으며 0.5 mg/mL 농도의 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | 0.5–5 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JES6-1A2 |
| Immunogen | A recombinant protein of mouse IL-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Tosil
- Cellular location: Secreted
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine essential for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7).
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for precise gene expression.
Disruption of the IL-2 gene in mice leads to an ulcerative colitis-like disease, highlighting its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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