Thermo Fisher Scientific PSMD5 Polyclonal Antibody
PSMD5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot 및 면역세포염색(ICC/IF)에 적합합니다. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관합니다. 인간 프로테아좀 19S 서브유닛 S5b를 검출합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: L(485) S E G P Y Y V K P V S T T A V E G A E(504) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2170773 |
Product Specific Information
PA1-975 detects purified human proteasome 19S subunit S5b.
PA1-975 has been successfully used in Western blot procedures.
By Western blot, this antibody detects an ~55 kDa protein representing purified human proteasome 19S subunit S5b.
PA1-975 immunizing peptide corresponds to amino acid residues 485–504 from human proteasome 19S subunit S5b protein.
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits—two rings of seven alpha subunits and two rings of seven beta subunits.
The 19S regulator includes a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome variant processes class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator base.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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