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Thermo Fisher Scientific KLHL12 Monoclonal Antibody (OTI1E6), TrueMAB
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Human KLHL12 단백질(aa 177-405)에 특이적인 Mouse IgG1 단클론 항체로 Western blot에 적합. 1 mg/mL 농도의 액상 형태로 PBS/BSA/glycerol buffer에 보존. CUL3 기반 E3 ligase 복합체 연구 및 Wnt 신호 조절 분석에 활용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 02. 오전 12:26
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Thermo Fisher Scientific TA803164 KLHL12 Monoclonal Antibody (OTI1E6), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
Thermo Fisher Scientific · Thermo Fisher Scientific KLHL12 Monoclonal Antibody (OTI1E6), TrueMAB
Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E6 |
| Immunogen | Human recombinant protein fragment (aa 177–405 of human KLHL12) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KLHL12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via targeted ubiquitination and subsequent proteolysis of DVL3.
Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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