Thermo Fisher Scientific FMO2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 210-470 of human FMO2 (NP_001451.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FMO2,uniProtId:Q99518-1,ncbiNodeId:9606,antigenRange:210-470,antigenLength:535,antigenImageFileName:PA5-109732_FMO2_Q99518-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109732_FMO2_Q99518-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855143

Product Specific Information

Immunogen sequence: VFISTRHGTW VMSRISEDGY PWDSVFHTRF RSMLRNVLPR TAVKWMIEQQ MNRWFNHENY GLEPQNKYIM KEPVLNDDVP SRLLCGAIKV KSTVKELTET SAIFEDGTVE ENIDVIIFAT GYSFSFPFLE DSLVKVENNM VSLYKYIFPA HLDKSTLACI GLIQPLGSIF PTAELQARWV TRVFKGLCSL PSERTMMMDI IKRNEKRIDL FGESQSQTLQ TNYVDYLDEL ALEIGAKPDF CSLLFKDPKL AVRLYFGPCN S

Target Information

The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.