Thermo Fisher Scientific FLT4 Polyclonal Antibody
FLT4(VEGFR3)에 특이적인 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에 반응. ICC/IF 및 ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 혈관 및 림프관 발달 연구용으로 적합.
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- PA5109731
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Thermo Fisher Scientific FLT4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1174–1363 of human VEGFR3/FLT4 (NP_8915552) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855142 |
Product Specific Information
Immunogen sequence:
QGRGLQEEEE VCMAPRSSQS SEEGSFSQVS TMALHIAQAD AEDSPPSLQR HSLAARYYNW VSFPGCLARG AETRGSSRMK TFEEFPMTPT TYKGSVDNQT DSGMVLASEE FEQIESRHRQ ESGFSCKGPG QNVAVTRAHP DSQGRRRRPE RGARGGQVFY NSEYGELSEP SEEDHCSPSA RVTFFTDNSY
Target Information
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specific lymphatic endothelial receptor VEGFR-3. Inactivation of the VEGFR-3 gene in mice results in defective blood vessel development during early embryogenesis, leading to abnormal vessel organization and cardiovascular failure. VEGFR3 plays an essential role in the development of the embryonic cardiovascular system before lymphatic vessel formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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