Thermo Fisher Scientific CDKN2B Monoclonal Antibody (OTI2D11), TrueMAB
CDKN2B 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, Flow cytometry에 적합합니다. HEK293T 세포에서 발현된 full-length human CDKN2B 단백질로 면역화되었습니다. 동결건조 형태이며, PBS 완충액에 8% 트레할로스가 포함되어 있습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D11 |
| Immunogen | Full length human recombinant protein of human CDKN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The INK4 family includes four proteins (p15^INK4b, p16^INK4a, p18^INK4c, and p19^INK4d) that bind and inhibit CDK4 and CDK6 but not other CDKs such as cyclin E-Cdk2, cyclin A-Cdk2, or cyclin B-Cdk1.
These proteins are expressed in tissue-specific patterns, indicating non-redundant roles.
p18^INK4c is expressed during the G1 to S transition of the eukaryotic cell cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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