Thermo Fisher Scientific UCP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 112-211 of human UCP2 (NP_003346.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UCP2,uniProtId:P55851-1,ncbiNodeId:9606,antigenRange:112-211,antigenLength:309,antigenImageFileName:PA5-120884_UCP2_P55851-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120884_UCP2_P55851-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.82 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914456

Product Specific Information

Positive test controls include: Raji, A-549, HT-29, RAW264.7, Mouse heart, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.

Immunogen sequence: EHASIGSRLL AGSTTGALAV AVAQPTDVVK VRFQAQARAG GGRRYQSTVN AYKTIAREEG FRGLWKGTSP NVARNAIVNC AELVTYDLIK DALLKANLMT

Target Information

UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.