Thermo Fisher Scientific UCP2 Polyclonal Antibody
Thermo Fisher Scientific의 UCP2 Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit IgG 기반 항체입니다. Western blot과 ELISA에 적합하며, 미토콘드리아 내막 단백질 UCP2 검출에 사용됩니다. 고순도 Affinity Chromatography 정제 및 안정적 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 112–211 of human UCP2 (NP_003346.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.82 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914456 |
Product Specific Information
- Positive test controls: Raji, A-549, HT-29, RAW264.7, Mouse heart, Rat heart
- Target localization: Mitochondrion inner membrane, Multi-pass membrane protein
Immunogen sequence:
EHASIGSRLL AGSTTGALAV AVAQPTDVVK VRFQAQARAG GGRRYQSTVN AYKTIAREEG FRGLWKGTSP NVARNAIVNC AELVTYDLIK DALLKANLMT
Target Information
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells.
UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle.
UCP2 is thought to play a role in non-shivering thermogenesis, obesity, and diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-120884_UCP2_P55851-1_Rabbit.svg, PA5-120884_UCP2_P55851-1_Rabbit_PDP.jpeg)
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