Thermo Fisher Scientific QSOX1 Polyclonal Antibody
Thermo Fisher Scientific QSOX1 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 Rabbit IgG 항체입니다. Western blot 및 ELISA에 사용 가능하며, 고순도 Affinity Chromatography로 정제되었습니다. 세포 내 Golgi 및 분비 단백질 검출에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–330 of human QSOX1 (NP_001004128.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.671 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914453 |
Product Specific Information
Positive test controls include:
- NCI-H460
- U-251MG
- Mouse heart
Localization of target:
- Golgi apparatus membrane
- Secreted
- Single-pass membrane protein
- Extracellular space
Immunogen sequence:
MRRCNSGSGP PPSLLLLLLW LLAVPGANAA PRSALYSPSD PLTLLQADTV RGAVLGSRSA WAVEFFASWC GHCIAFAPTW KALAEDVKAW RPALYLAALD CAEETNSAVC RDFNIPGFPT VRFFKAFTKN GSGAVFPVAG ADVQTLRERL IDALESHHDT WPPACPPLEP AKLEEIDGFF ARNNEEYLAL IFEKGGSYLG REVALDLSQH KGVAVRRVLN TEANVVRKFG VTDFPSCYLL FRNGSVSRVP VLMESRSFYT AYLQRLSGLT REAAQTTVAP TTANKIAPTV WKLADRSKIY MADLESALHY ILRIEVGRFP VLEGQRLVAL
Target Information
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1.
Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation.
The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins.
QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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