Thermo Fisher Scientific CFLAR Monoclonal Antibody (OTI1B1), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

FLIP (CFLAR) is an apoptosis regulator protein that serves as a key link between cell survival and cell death pathways in mammalian cells.
It inhibits TNFRSF6-mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC), blocking further recruitment and processing of caspase-8.
Full-length and shorter isoforms can either induce or inhibit TNFRSF-triggered apoptosis.
Lacks enzymatic (caspase) activity.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.