Thermo Fisher Scientific MAGE-1 Polyclonal Antibody
인간 및 랫트 반응성의 MAGE-1 폴리클로날 항체로 다양한 면역분석(WB, IHC, ICC, ELISA)에 사용 가능. 정제된 Rabbit IgG 형태로 1 mg/mL 농도. 암 면역치료 연구용으로 적합하며, -20°C에서 보관.
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Thermo Fisher Scientific MAGE-1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MAGE-1 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, cytolytic CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes, identified as melanoma-associated antigens (MAAs).
MAGE-1 is expressed in a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas) but not in normal tissues.
Therefore, the encoded antigen may serve as a marker for early detection and as a target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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