Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (11C3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

11C3

Immunogen

Recombinant protein within Human HLA Class 1 ABC aa 1-362 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HLA-ABC,uniProtId:P04439-1,ncbiNodeId:9606,antigenRange:1-362,antigenLength:365,antigenImageFileName:MA5-34926_HLA-ABC_P04439-1_House_mouse.svg,antigenImageFileNamePDP:MA5-34926_HLA-ABC_P04439-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:HLA-ABC,uniProtId:P01889-1,ncbiNodeId:9606,antigenRange:1-362,antigenLength:362,antigenImageFileName:MA5-34926_HLA-ABC_P01889-1_House_mouse.svg,antigenImageFileNamePDP:MA5-34926_HLA-ABC_P01889-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:HLA-ABC,uniProtId:P10321-1,ncbiNodeId:9606,antigenRange:1-362,antigenLength:366,antigenImageFileName:MA5-34926_HLA-ABC_P10321-1_House_mouse.svg,antigenImageFileNamePDP:MA5-34926_HLA-ABC_P10321-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2848832

Product Specific Information

Positive Control: Hela, 293T.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.