Thermo Fisher Scientific HADHA Polyclonal Antibody
Thermo Fisher Scientific의 HADHA Polyclonal Antibody는 인간 HADHA 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF, IP 등 다양한 실험에 사용 가능하며, 미토콘드리아 내 표적 단백질 검출에 적합합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific HADHA Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 484–763 of human HADHA (NP_000173.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.89 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913774 |
Product Specific Information
- Positive test controls: 293T, K-562
- Subcellular localization: Mitochondrion
Immunogen Sequence:
IAAVSKRPEK VIGMHYFSPV DKMQLLEIIT TEKTSKDTSA SAVAVGLKQG KVIIVVKDGP GFYTTRCLAP MMSEVIRILQ EGVDPKKLDS LTTSFGFPVG AATLVDEVGV DVAKHVAEDL GKVFGERFGG GNPELLTQMV SKGFLGRKSG KGFYIYQEGV KRKDLNSDMD SILASLKLPP KSEVSSDEDI QFRLVTRFVN EAVMCLQEGI LATPAEGDIG AVFGLGFPPC LGGPFRFVDL YGAQKIVDRL KKYEAAYGKQ FTPCQLLADH ANSPNKKFYQ
Target Information
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long-chain fatty acids. The mitochondrial membrane-bound heterocomplex consists of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Mutations in this gene cause trifunctional protein deficiency or LCHAD deficiency. The alpha and beta subunit genes are located adjacent to each other in a head-to-head orientation in the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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