Thermo Fisher Scientific Plasma Kallikrein Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ELISA에 적합. KLKB1(aa 391-500) 항원으로 제작되었으며, 액상 형태로 1.1 mg/mL 농도. PBS/glycerol buffer에 보관하며 -20°C에서 보존.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Plasma Kallikrein Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 391–500 of KLKB1 (NP_000883.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913775 |
Product Specific Information
Positive test controls include: HT-29, 293T, BxPC-3, Mouse liver, Mouse pancreas, Rat liver.
The target is usually found in the following locations: Secreted.
Immunogen sequence:
IVGGTNSSWG EWPWQVSLQV KLTAQRHLCG GSLIGHQWVL TAAHCFDGLP LQDVWRIYSG ILNLSDITKD TPFSQIKEII IHQNYKVSEG NHDIALIKLQ APLNYTEFQK
Target Information
Plasma prekallikrein is a glycoprotein involved in blood coagulation, fibrinolysis, kinin generation, and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain.
Plasma prekallikrein is converted to plasma kallikrein by factor XIIa via cleavage of an internal Arg-Ile bond, resulting in a heavy and light chain linked by a disulfide bond.
- The heavy chain contains four tandem repeats with apple domains, essential for surface-dependent pro-coagulant activity.
- The light chain contains the active catalytic domain, homologous to trypsin-like serine proteases.
Deficiency of plasma prekallikrein leads to prolonged activated partial thromboplastin time.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.