Thermo Fisher Scientific ADAT3 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific ADAT3 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB)

Tested Dilution

• 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MEPAPGLVEQ PKCLEAGSPE PEPAPWQALP VLSEKQSGDV ELVLAYAAPV LDKRQTSRLL KEVSALHPLP AQPHLKRVRP SRDAGSPHAL EMLLCLAGPA SGPRSLAELL PRPAVDPRGL GQPFLVPVPA RPPLTRGQFE EARAHWPTSF HEDKQVTSAL AGRLFSTQER AAMQSHMERA VWAARRAAAR GLRAVGAVVV DPASDRVLAT GHDCSCADNP LLHAVMVCVD LVARGQGRGT YDFRPFPACS FAPAAAPQAV RAGAVRKLDA DEDGLPYLCT GYDLYVTREP CAMCAMALVH ARILRVFYGA PSPDGALGTR FRIHARPDLN HRFQVFRGVL EEQCRWLDPD T

Target Information

This gene encodes a subunit of a tRNA-specific adenosine deaminase. This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon. A mutation in this gene causes a syndrome characterized by intellectual disability and strabismus. This gene shares its 5' exon with the overlapping gene, secretory carrier membrane protein 4.
ADAT3 (Adenosine Deaminase tRNA Specific 3) is a protein-coding gene. Diseases associated with ADAT3 include Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies and Cone-Rod Dystrophy 10.
Among its related pathways are tRNA processing and Processing of Capped Intron-Containing Pre-mRNA. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is ADAT2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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