Thermo Fisher Scientific Decorin Polyclonal Antibody
Thermo Fisher Scientific의 Decorin Polyclonal Antibody는 인간 Decorin 단백질을 인식하는 Rabbit IgG 기반 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA527370
- 판매단위
- pk
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Thermo Fisher Scientific Decorin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | – |
| in situ PLA (PLA) | – | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Horse, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–192 of Human Decorin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544846 |
Product Specific Information
- Recommended positive controls: A549, H1299
- Predicted reactivity: Mouse (82%), Rat (80%), Dog (91%), Pig (88%), Rabbit (90%), Sheep (86%), Chimpanzee (100%), Bovine (87%), Guinea pig (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Decorin is a member of the small leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-β. Decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154–Leu155 of the decorin core protein.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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