Thermo Fisher Scientific DTNBP1 Polyclonal Antibody
DTNBP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–351 of Human Dysbindin (DTNBP1, UniProt ID: Q96EV8-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544847 |
Product Specific Information
- Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, mouse brain, rat brain
- Predicted reactivity: Pig (86%), Chicken (80%), Sheep (86%), Bovine (87%)
- Store as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Dtnbp1 is involved in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.
In mouse, it is part of the biogenesis of lysosome-related organelles complex 1 (BLOC-1) and binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC).
Mutations are associated with Hermansky-Pudlak syndrome type 7, and the protein may also be linked to schizophrenia.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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