Thermo Fisher Scientific IL36B Recombinant Rabbit Monoclonal Antibody (025)
마우스 IL36B/IL1F8 단백질을 인식하는 재조합 토끼 단일클론 항체. ELISA에 적합하며, 높은 특이성과 일관된 품질 제공. 방부제 무첨가로 필요 시 아지드 추가 권장. 단기 4°C, 장기 -20°C 보관.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 025 |
| Immunogen | Recombinant Mouse IL36B/IL1F8 protein (Met1–Lys183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786454 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
This antibody has specificity for Mouse IL36B/IL1F8.
Target Information
IL-36B is a member of the interleukin 1 cytokine family. Its gene, along with eight other IL-1 family genes, forms a cytokine gene cluster on chromosome 2.
IL-36B activates the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP.
Like IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, although the cleavage mechanism is currently unknown.
IL-36 cytokines are suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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