Thermo Fisher Scientific IL36B Recombinant Rabbit Monoclonal Antibody (025)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Mouse IL36B/IL1F8.

Target Information

IL-36B is a member of the interleukin 1 cytokine family. Its gene, along with eight other IL-1 family genes, forms a cytokine gene cluster on chromosome 2.
IL-36B activates the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP.
Like IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, although the cleavage mechanism is currently unknown.
IL-36 cytokines are suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.