Thermo Fisher Scientific MYCN Monoclonal Antibody (OTI1B5), TrueMAB
MYCN 단백질을 표적으로 하는 mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. 인간 및 랫트에 반응하며, carrier-free 형태로 제공되어 conjugation 실험에 적합합니다. 신경모세포종 연구 등 MYCN 관련 연구에 유용합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 229–464 of human MYCN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
N-Myc protein is a member of the MYC family of transcription factors containing a basic helix-loop-helix (bHLH) domain.
It functions complementarily to C-Myc in cellular growth and differentiation processes.
MYCN gene amplification and overexpression occur in approximately 20% of neuroblastomas, correlating with advanced disease stage, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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