Thermo Fisher Scientific BMP3 Monoclonal Antibody (D3)
BMP3 단백질을 인식하는 D3 클론의 Mouse IgG1 단일클론 항체로 Western Blot과 IHC(Paraffin)에 적합합니다. Sheep 반응성, Protein A/G 정제, PBS+50% glycerol 보존. 골형성 관련 연구용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Sheep |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D3 |
| Immunogen | Recombinant protein Bone Morphogenetic Protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899041 |
Target Information
The Bone Morphogenetic Proteins (BMPs) belong to the TGF-Beta superfamily. BMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal, epithelial, hematopoietic, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary, and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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