Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser79) Polyclonal Antibody
Phospho-Acetyl-CoA Carboxylase (Ser79)에 특이적인 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western Blot과 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S79 of human ACC1 (NP_9421331) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901819 |
Product Specific Information
- Positive Samples: 293T
- Immunogen Sequence: SMSGL
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by separate genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is controlled at transcriptional and translational levels, and regulated in the short term by phosphorylation/dephosphorylation of serine residues and by allosteric transformation via citrate or palmitoyl-CoA.
Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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