Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser79) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive Samples: 293T
• Immunogen Sequence: SMSGL

Target Information

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by separate genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is controlled at transcriptional and translational levels, and regulated in the short term by phosphorylation/dephosphorylation of serine residues and by allosteric transformation via citrate or palmitoyl-CoA.
Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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