Thermo Fisher Scientific TBXA2R Polyclonal Antibody
TBXA2R 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 검증됨. 인간 및 유인원과 높은 서열 유사성을 가짐. 혈소판 응집 및 심혈관 질환 연구에 적합. 냉장 또는 -20°C 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human TBXA2R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2551610 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey, Marmoset: 100%
- Dog, Panda: 95%
- Elephant: 90%
- Bat, Bovine, Pig: 85%
- Opossum: 80%
Target Information
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily.
TBXA2R plays an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation.
Thromboxane A2 has been implicated in myocardial infarction, stroke, and asthma.
Additionally, thromboxane-prostanoid receptors are associated with the pathogenesis of cardiovascular diseases.
Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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