Thermo Fisher Scientific Human IFN-alpha A (alpha 2a) (Carrier-Free) Recombinant Protein
인간 IFN-alpha A (alpha 2a) 재조합 단백질로 항바이러스 면역 반응 연구에 사용. E. coli 발현, 95% 이상 순도, 고활성(4.0x10e8 units/mg). ELISA, WB, IHC 등 다양한 실험에 적합. -80°C 보관, 드라이아이스 배송.
- 카탈로그번호
- PHC4814
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- ELISA: Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Molecular Weight | 19.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95% by SDS-PAGE |
| Activity | Specific activity = 4.0×10⁸ units/mg; measured by cytopathic effect inhibition assay (Rubinstein et al., 1981; Familletti et al., 1981). Activity determined using bovine MDBK cells challenged with vesicular stomatitis virus (VSV). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry ice |
Product Specific Information
- Dilution Recommendation: Further dilutions should be made in medium or buffered solution containing carrier protein such as PBS with 0.1% BSA.
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. Interaction of IFN-alpha with its receptor components activates multiple signaling pathways involved in innate immune responses against viral infection.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons consist of 14 alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including mammals, birds, reptiles, and fish.
Produced primarily by plasmacytoid dendritic cells, IFN alpha is a potent component of the antiviral innate immune response and modulates adaptive immunity. Dysfunctions are associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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